Tyrosine kinase receptor A (Trk-A) is a member of the neurotrophic tyrosine kinase receptor family which includes three members: Trk-A, Trk-B and Trk-C. Trk-A is involved in the development and maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic neurons.

產品簡介SpeciesHumanProtein ConstructionTrkA (Ala34-Pro407)Accession # P04629Purity> 95% as analyzed by SDS-PAGEEndotoxin Level< 0.2 EU/μg of protein by gel clotting methodBiological ActivityED50 < 1.0 μg/ml, measured in a neutralization assay in the presence of 10.0 ng/ml human β-NGF using TF-1 Cells.Expression SystemHEK 293Apparent Molecular Weight65~85 kDa, on SDS-PAGE under reducing conditions.FormulationLyophilized after extensive dialysis against PBS.ReconstitutionIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.Storage & StabilityUpon receiving, this product remains stable for 6 months at lower than -70°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.